ALISHA:

I’m an artist. I’m a hairstylist and I own my own salon. I get a lot of happiness when someone feels good in their new haircut.

Cutting hair and helping others has always felt like my purpose. It’s also important for me to find inspiration in life.

I use my painting to escape and to be inspired. I’m in the moment, focused on what I’m creating.

Drip painting is a way of painting that you pour paint straight onto the canvas. There’s just so many different ways to create something. No two paintings ever turn out exactly the same.

I started painting to process everything going on in my life when I was diagnosed with cancer.

When I was 30, my doctor found a tumor pressing up against my reproductive organs. I underwent some tests, including a Pap smear, and it showed I had cervical cancer.

I received my initial treatment and, afterwards, my doctor said there was no more signs of cancer. For 22 years, I received regular scans and testing.

One day I experienced unexplained bleeding, and I knew I needed to see my doctor. A biopsy showed that my cervical cancer was back.

After that diagnosis, I was devastated. I was scared. I was scared of dying, I just really felt alone.

After many rounds of chemotherapy, the treatment stopped working and I wasn’t sure what to do next.

I started to get discouraged. It was so scary and so hard. I just needed something, an outlet, to leave it. I turned to my art to process the emotions I was feeling.

It’s just so beautiful to create something and then, just, you don’t think about it. You don’t think about anything, no problems, no nothing. It’s just creating.

The art is taking over. I let my emotions spill out onto the canvas. Immersing myself into my art allowed me to stay positive during this time.

I knew I wasn’t ready to give up. I knew it was going to be a fight, but I made a choice to keep trying. That’s when my doctor recommended Tivdak.

Narrator:

TIVDAK (tisotumab vedotin-tftv) 40mg, for injection is a prescription medicine used to treat adults with cervical cancer that has returned or has spread to other parts of the body, and who have received chemotherapy that did not work or is no longer working.

Alisha:

My first reaction when I heard about TIVDAK was I had to do it.

My doctor told me about the serious side effects of TIVDAK. I was concerned about the side effects, but I was also concerned about losing my fight with cancer. Giving up was not an option.

After talking with my doctor, I learned about the steps that can help reduce the risk of eye problems. I felt more confident in my knowledge, and I decided to start treatment on TIVDAK.

Narrator:

Eye problems are common with TIVDAK and can be severe. TIVDAK can cause changes to the surface of your eye that can lead to dry eyes, eye redness, eye irritation, corneal ulcers, blurred vision, and severe vision loss.

Serious side effects of TIVDAK may include eye problems, nerve problems (peripheral neuropathy), bleeding problems (hemorrhage), lung problems, and severe skin reactions. TIVDAK can harm your unborn baby.

These are not all the side effects of TIVDAK. Please see the end of this video for more details about side effects and visit TIVDAK.com/resources to review the Important Facts about TIVDAK including the IMPORTANT WARNING.

Alisha:

I visit an eye specialist before every infusion. After setting up a routine with my eye specialist, I feel good about the process.

My treatment takes about 30 minutes. During that time, I like to sit back and listen to music.

I had my first scan a few months after starting treatment. It showed that my cervical cancer was responding to treatment.

I continue to go in for my infusions every three weeks. I experience some side effects, like nausea, dry, irritated eyes, but my doctor helped me manage them.

There are additional side effects that you might experience on treatment. This is just my experience, everyone’s experience on TIVDAK is different.

I’m so happy that I can continue finding my purpose by helping others.

When cancer patients come into my salon, I love helping them feel confident with how they look.

I now approach my art with a new energy. I’m able to keep trying new things for inspiration.

I love discovering all the things I’m able to do through my art.

VOICEOVER:

What is TIVDAK?

TIVDAK is a prescription medicine used to treat adults with cervical cancer:

• that has returned or has spread to other parts of the body, and
• who have received chemotherapy that did not work or is no longer working.

Important Safety Information

What is the most important information I should know about TIVDAK?

Eye problems are common with TIVDAK and can be severe. TIVDAK can cause changes to the surface of your eye that can lead to dry eyes, eye redness, eye irritation, corneal ulcers, blurred vision, and severe vision loss. Tell your healthcare provider if you develop new or worsening vision changes or eye problems during treatment.

Your healthcare provider will send you to an eye specialist to check your eyes before you start treatment with TIVDAK, before each infusion for your first 9 infusions of TIVDAK, and as needed for any new or worsening signs or symptoms of eye problems. Your healthcare provider will ask if you have any signs or symptoms of eye problems before each infusion. You will be referred to an eye specialist for any new or worsening signs or symptoms of eye problems.

Your healthcare provider will prescribe 3 different types of eye drops before you start treatment with TIVDAK. Bring the eye drops with you to each infusion and use them as directed by your healthcare provider to reduce your risk of eye problems:

• Use 1 drop of steroid eye drops in each eye before each infusion and continue to use your eye drops 3 times a day for 3 days after each infusion
• Use vasoconstrictor eye drops right before each infusion
• Use lubricating eye drops throughout treatment and for 30 days after your last dose of TIVDAK

Do not wear contact lenses throughout your treatment with TIVDAK unless you are told to use them by your eye specialist.

What are the possible side effects of TIVDAK?

Serious side effects of TIVDAK may include:

Eye Problems. See “What is the most important information I should know about TIVDAK?”

Nerve problems (peripheral neuropathy) are common with TIVDAK and can be serious. Tell your healthcare provider right away if you have new or worsening numbness or tingling in your hands or feet or muscle weakness.

Bleeding problems (hemorrhage) are common with TIVDAK and can be serious. Tell your healthcare provider or get medical help right away if you have signs or symptoms of bleeding during treatment with TIVDAK, including blood in your stools or black stools (looks like tar), blood in your urine, cough up or vomit blood, unusual vaginal bleeding, or any unusual or heavy bleeding.

Lung problems. TIVDAK may cause severe or life-threatening inflammation of the lungs that can lead to death. Tell your healthcare provider right away if you have new or worsening symptoms, including trouble breathing, shortness of breath, or cough.

Severe skin reactions. TIVDAK may cause severe or life-threatening skin reactions that can lead to death. Tell your healthcare provider or get medical help right away if you have signs or symptoms of a severe skin reaction during treatment with TIVDAK, including:

• Skin reactions that look like rings (target lesions)
• Rash or itching that continues to get worse
• Blistering or peeling of the skin
• Painful sores or ulcers in your mouth, nose, throat, or genital area
• Fever or flu-like symptoms
• Swollen lymph nodes

The most common side effects of TIVDAK include:

• Decreased red blood cell counts
• Numbness or tingling in your hands or feet
• Eye problems (conjunctival disorders)
• Nausea
• Tiredness
• Changes in liver function blood tests
• Nosebleed
• Hair loss (alopecia)
• Bleeding (hemorrhage)

Your healthcare provider may decrease your dose of TIVDAK, temporarily stop, or completely stop treatment if you have side effects.

What should I tell my healthcare provider before receiving TIVDAK?

Tell your healthcare provider about all your medical conditions, including if you:

• have a history of vision or eye problems
• have numbness or tingling in your hands or feet
• have bleeding problems
• have liver problems
• are pregnant or plan to become pregnant; TIVDAK can harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with TIVDAK
• are breastfeeding (nursing) or plan to breastfeed. It is not known if TIVDAK passes into your breast milk. Do not breastfeed during treatment and for at least 3 weeks after the last dose of TIVDAK

Females who can become pregnant:

• Your healthcare provider should do a pregnancy test before you start treatment with TIVDAK
• Use an effective method of birth control during your treatment and for at least 2 months after the last dose of TIVDAK

Males with female partners who can become pregnant:

• Use effective birth control during treatment and for 4 months after the last dose of TIVDAK

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking TIVDAK with certain other medicines may cause side effects.

These are not all of the possible side effects of TIVDAK. Discuss side effects with your healthcare provider. You may report side effects to FDA at 1-800-FDA-1088.

Please see the full Prescribing Information with Medication Guide about TIVDAK including an IMPORTANT WARNING at TIVDAK.com.